In any given urban center, be it New York or San Francisco (or Rome or Tokyo for that matter) there will always be a population of the "A B normal" (Abby Normal, aka crazy). It's just that in Paris, Frankfurt, New York, Chicago, Beijing and so on strange remains strange, it is the outlier in the overall population. In San Francisco, strange is the new normal. Now whether that is good or bad is a matter of personal preference and tolerance for the strange.
photo - it's from Chicago 2015. Eugene was always a place where hippies were welcomed when the students were out of town.